Shank features a cooperative campaign designed to be played locally, which is a prequel to the single-player campaign. The multiplayer allows players to play as Shank and his partner-in-crime named Falcone. In this mode players are often required to work as a team to accomplish objectives, such as defeating level bosses. Players can combine moves for special attacks with the characters performing together. Also available is the ability to revive a fallen teammate should they die in combat.
Plot
The story of Shank is told in two parts, single-player campaign, and a cooperative campaign, which serves as a prelude to the former. It follows the character Shank (voiced by Marcel Davis) from his time as a hitman in the mob through his revenge on the same mob for the murder of his girlfriend Eva (voiced by Becky Poole).
Cooperative campaign
The cooperative campaign begins with Shank and fellow hitman Falcone (voiced by Gavin Cummins) as they head to Cassandra's (voiced by Sheila Goold) strip club, which has been overrun by a biker gang. As they arrive she is kidnapped by the biker leaders. Shank and Falcone chase them to a back alley and kill one, leaving the other for Cassandra. The pair then head to a wrestling match that their mob boss Cesar had rigged. The Butcher (voiced by Dave White) was supposed to lose the fight, but the wrestler instead decides to defeat his opponent. Shank and Falcone are ordered to teach the Butcher a lesson. Later, Cesar phones the two hitmen and asks them to go and oppose a priest and the members of his congregation. They succeed in kidnapping the priest, Father Gomez (voiced by Steve Lange), taking him to Cesar (voiced by Dave White) and his cousin Angelo (voiced by Tim Gouran). Angelo shoots the priest in the face, much to Shank's disapproval; he then dons the dead priest's garments and takes his place in order to make the murder go undetected.
Afterward, Falcone calls Shank about an important hit: the deputy mayor is in town and he must be eliminated. By taking him out, the mob will be able to gain control. Shank and Falcone kill the deputy's final bodyguard, and are about to take the deputy out when Eva is taken hostage. Suddenly Shank is full of doubt, and is not able to pull the trigger. Rudy (voiced by David Goldstein), Cesar's personal assistant, kills the deputy mayor, threatening to kill Eva since she's deemed as a nuisance. Shank quickly dives in front of her and kills him. Realizing they must flee, Eva and Shank drive off into the sunset. The player then hears the voice of Cesar who tells his assassins to find and kill them.
Single-player campaign
The single player campaign begins as Shank walks into a bar looking for vengeance for Eva, his murdered girlfriend. He asks the bartender where he can find a wrestler named the Butcher. He pulls down a poster of a fight that mentions the Butcher's next fight. As he leaves the bartender reports to Cesar about Shank's return. As Shank makes his way to the wrestling arena, the player learns through flashbacks that the Butcher had kidnapped Eva. Shank arrives at the arena and confronts the Butcher, killing him. He soon realizes that he killed an impersonator, as the dead fighter does not have the same tattoo as the Butcher. He discovers that the Butcher is in another town and travels there.
After a violent train ride Shank arrives at a meat factory, the Butcher's hideout. The Butcher reveals that he killed Eva and taunts Shank, stating that he enjoyed every second of it. Shank and the Butcher fight, with Shank finally choking him with a chain. He then makes his way to Club Stardust, a strip club owned by Cassandra. Shank meets with Cassandra at which point a flashback shows that as Cassandra was about to kill Eva with her katana, Shank stopped her, slicing the right of her face and leaving a large scar. He kills Cassandra and escapes the club. In a nearby bar he encounters a man from the Venom gang named Mello (voiced by Eric Reidman) who has information. The player learns through another flashback that Shank used to be part of a mob ruled by a man named Cesar. However, when Cesar asked Shank to kill Eva as a test of loyalty, Shank refused and Cesar ordered his top men to track down and kill them both.
He follows an ex-friend from his former mobster life to track down "Father" Angelo. He soon catches up with his prey, severs his left arm and tells him to tell Angelo that he's coming. Shank follows the trail of blood left by the mobster which leads to a church. At the church Shank has another flashback, which shows that Angelo lit Shank's house on fire, ensuring Eva could not be saved. As Shank fights through the church, Angelo attacks him with a rocket launcher. Shank battles him, gaining the upper hand, but Angelo fires a rocket causing a church bell to fall on Shank, knocking him unconscious. He wakes up strapped to an electric chair, face to face with Cesar. After Cesar leaves Shank frees himself, then ties Angelo to the chair and electrocutes him.
Shank pursues Cesar to his villa, where the final showdown begins. As they fight, more of his past is revealed. Shank would have obeyed the order to kill Eva, but upon arriving Eva revealed that she was carrying his child. Shank explains that Cesar had always taught him the importance of family and so he did not kill her. Cesar replies that if he had known this things could have gone differently. As the fight nears its end, Shank is stabbed and shot multiple times in the chest. Despite this, he still manages to kill Cesar. The game ends as Shank walks towards the sunset, his revenge fulfilled.