Shinra Kuonji (久遠寺 森羅 Kuonji Shinra)
Voiced by: Shizuka Itō (credited in PC as Rina Misaki)
Eldest sister of the Kuonji siblings, she has a habit of teasing the people she likes and a fondness for cute things particularly Ren and her own sister, Miyu. Her favorite animal is a panda because she finds how they are black and white "cute". Despite her relatively young age she has made a name for herself as a famous orchestral conductor. On hiring Ren and Mihato, Shinra tells them not to refer to Miyu with honorifics.
Venis (朱子 Benisu)
Voiced by: Hyo-sei (credited in PC as Erena Kaibara)
Venis is the Kuonji head maid and Shinra's personal attendant. She has a violent short temper. Her name has a similar phonetic sound to "penis" when said in Japanese. This is shown to greatly aggravate her when the Uesugi siblings make fun of it. Venis grew up in a poor section of an unnamed European city, working at a relative's restaurant while learning to cook, learning to fight while protecting herself from those who would try to grab her, and teaching herself math in the streets. After the restaurant closed, she was picked up off the streets by the Colonel, who was impressed by her skill in cooking and brought her to work at the Kuonji house. She values Shinra's praise and attention above all else because she feels that Shinra gives her a reason to live. She initially clashes with Ren, who refers to her as Benikō (ベニ公) in order to prevent himself from laughing at her name. However when the two are kidnapped and Ren purposely aggravates their kidnappers to divert their attention from her, she begins to see him in a new light.
Miyu Kuonji (久遠寺 未有 Kuonji Miyu)
Voiced by: Yūko Gotō (credited in PC as Shino Kujō)
Second oldest of the Kuonji and referred to as a "loli" by Shinra due to her short and childish appearance. Despite her size and figure, she is actually in her twenties. She constantly protests against being treated as child and molested by Shinra, but she gives in when the treatment has a small plus side to it (candy, presents, games, hugs, etc.) Miyu is a shotacon though she also seems attracted to Ren as well. She is also the smartest of the sisters, already having graduated from college. Miyu claims to have an I.Q. of 240 and earns millions by selling her patented inventions, thus she has a lot of free time to idle around. She created De Niro, an egg shaped robot. Miyu was the first of the Kuonji sisters whom Ren meets when Miyu passes out in the street.
Mihato Uesugi (上杉 美鳩 Uesugi Mihato)
Voiced by: Hitomi (credited in PC as Minami Hokuto)
Ren's older half sister who ran away with him. She occasionally needs glasses, is known to hide items in forty-nine different places on her body and has admitted to having a "Brother Complex". After she and Ren become part of the servant staff, she shows signs of being lonely without him near her, even though they are in the same building. She is sometimes jealous that Ren pays attention to girls other than her and thinks of ways of removing the person who is drawing his attention away from her, but is usually stopped before anything happens (played for comedic effect in the anime). She works as Miyu's personal maid. Ren calls Mihato Hato-nee and she refers to him as Ren-chan.
Yume Kuonji (久遠寺 夢 Kuonji Yume)
Voiced by: Shizuka Minamori (credited in PC as Sora Amano)
The youngest of the Kuonji siblings and probably the most stereotypically average one among them as far as personality and personal problems go. Referring to herself with her own name (a typically childish trait), Yume is usually overlooked by her sisters. Only Natose and Ren pay her any serious attention. She is envious of Shinra's fondness of Miyu. Her hobbies include repairing radio antennas, reading manga, writing silly imaginative stories and collecting seashells. Her most noticeable feature is her shockingly pink hair.
Natose (南斗星)
Voiced by: Yū Asakawa (credited in PC as Misaki Kamishiro)
Natose is Yume's personal attendant and also the head of security for Kuonji mansion. She has blue hair and wears an eyepatch over her right eye. When in battle she takes a Muay Thai stance. She has a great love for food and is shown to have superhuman abilities when it comes to obtaining it. She grew up on an island together with a younger sister and brother, however she lost her family and her right eye in a tsunami. Ren astutely observes that she has always wished to have a younger sibling and thus calls her "big sis". Her name means "Southern Star" and she is depicted as almost dog-like (abundant energy, fetching the paper by leaping ridiculously high in the air, a love for meat products, a vicious fighter when her master is in need of her, incredibly loyal, but relatively easy to fool or distract, etc.)
Colonel (大佐 Taisa)
Voiced by: Yōsuke Akimoto (credited in PC as Zenshu Iwao)
The head butler, who used to be in the special forces, and whose name is Taijiri Yasushi. He believes himself to be incredibly handsome. In the anime, he frequently parodies other anime series, most notoriously Mobile Fighter G Gundam, as part of an in-joke referring to the fact that his and Ren's voice actors played major roles in that series. While very hard on Ren by pushing him to the limit in his butler training, he is in reality an honorable man and believes in Ren. The colonel's entire body is covered in scars from the time he spent in the special forces however they are usually covered by his butler uniform.
De Niro (デニーロ De Nīro)
Voiced by: Kazuya Tatekabe (credited as in PC as Ichibu Kachidoki)
Miyu's invention who serves as her attendant. An egg shaped robot with a mouth, not radio controlled but an advanced A.I that gives him free will and thoughts and also a bullying attitude. He likes to molest electronic appliances and sing karaoke, however his voice is designed as a powerful weapon which can cause serious brain damage to people. He also utilizes several other tools and weapons throughout the series including a drill and some form of a rocket system, however, it is unclear exactly with how many he has been equipped or of what they are capable.