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Foldit Download PC

  • Developer: UW Baker Lab
  • Release date: 2007
  • Platform: Windows (PC)
  • Genre: Puzzle
  • Version: Full Game
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    Foldit is an online puzzle video game about protein folding. It is part of an experimental research project developed by the University of Washington, Center for Game Science, in collaboration with the UW Department of Biochemistry. The objective of Foldit is to fold the structures of selected proteins as perfectly as possible, using tools provided in the game. The highest scoring solutions are analyzed by researchers, who determine whether or not there is a native structural configuration (native state) that can be applied to relevant proteins in the real world. Scientists can then use these solutions to target and eradicate diseases and create biological innovations. A 2010 paper in the science journal Nature credited Foldit's 57,000 players with providing useful results that matched or outperformed algorithmically computed solutions.

    History

    Rosetta

    Prof. David Baker, a protein research scientist at the University of Washington, founded the Foldit project. Seth Cooper was the lead game designer. Before starting the project, Baker and his laboratory coworkers relied on another research project named Rosetta to predict the native structures of various proteins using special computer protein structure prediction algorithms. Rosetta was eventually extended to use the power of distributed computing: The Rosetta@home program was made available for public download, and displayed its protein-folding progress as a screensaver. Its results were sent to a central server for verification.

    Some Rosetta@home users became frustrated when they saw ways to solve protein structures, but could not interact with the program. Hoping that humans could improve the computers' attempts to solve protein structures, Baker approached David Salesin and Zoran Popović, computer science professors at the same university, to help conceptualize and build an interactive program, a video game, that would appeal to the public and help efforts to find native protein structures.

    Foldit

    Video Review and Screenshots

    Foldit System Requirements

    • Operating System: Microsoft Windows XP / 7
    • Processor: Intel Pentium IV 1.6 GB or AMD2200
    • RAM: 512 MB
    • Video Card: 128 MB
    • Hard disk space: 200 MB


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